The program featured a wide range of actors, such as Will Ferrell, John C.Reilly, Jeff Goldblum, Zach Galifianakis, Will Forte, Patton Oswalt, Bob Odenkirk, David Cross, Fred Willard, Rainn Wilson, Fred Armisen, Paul Rudd and Ben Stiller to alternative comedians like Neil Hamburger, to former television stars like Alan Thicke, porn stars, celebrity look-alikes, impressionists and amateur actors found through Craigslist.
Schmidt, Palmer Scott, Tony Siragusa, Tom Skerritt, Paul St.Peter, Frank Stallone, Sydnee Steele, Ben Stiller, Peter Stormare, Fred Tatasciore, Alan Thicke, Scott Thompson, Danny Trejo, David Wain, Derek Waters, Fred Willard, Rainn Wilson, Ray Wise, Tommy Wiseau, and "Weird Al" Yankovic. The second season began airing on November 18, 2007. The third season began on July 27, 2008 and ended on September 28, 2008.It features several characters and segments seen in Tom Goes to the Mayor, such as Gibbons, the "Channel 5 Married News Team," and the Cinco Corporation with its variety of inefficient and tasteless products. The show featured a variety of celebrity cameos from actors, comedians, and musicians including Tucker Albrizzi, Fred Armisen, Robert Axelrod, Maria Bamford, Ed Begley, Jr., Corbin Bernsen, The Bird and the Bee, Karen Black, Michael Ian Black, Abbey Brooks, Le Var Burton, Michael Cera, Peter Cetera, Stephanie Courtney, David Cross, Elisha Cuthbert, Ted Danson, DJ Drez, Patrick Duffy, Richard Dunn, John Ennis, Tami Erin, Will Ferrell, Flight of the Conchords, Will Forte, Black Francis, Zach Galifianakis, Jeff Goldblum, Josh Groban, Michael Gross, Bill Hader, Neil Hamburger/Gregg Turkington, David Liebe Hart, Jonah Hill, Karen O, Sergio Kato, Tom Kenny, Tom Leykis, The Lonely Island, Doug Lussenhop, Ron Lynch, Aimee Mann, Marilyn Manson, Richard Marx, John Mayer, Jack Mc Brayer, A. Miles, Larry Miller, Cathy Mitchell, Matthew Moy, Dave Navarro, Bob Odenkirk, Patton Oswalt, Harout Pamboukjian, Steve Pemberton, Jerry Penacoli, Wendell Pierce, Brian Posehn, Sam Proof, Puscifer, Marion Ramsey, John C.New recurring characters and sketches include "Uncle Muscles Hour," a public-access television variety program hosted by a gravelly-voiced "Weird Al" Yankovic and Channel 5 News Correspondent Dr. Reilly, Paul Reubens, Daphne Rosen, Paul Rudd, William Sanderson, Steve Schirripa, Michael Q.The Uncle Muscles Hour: Casey and his Brother perform "Time Travel".
Cinco Family/Corporation: Cinco Toy's presents the "B'owl", half bat, half owl.It was writer and editor Doug Lussenhop who came up with the concept of this wholly unnecessary cross-species creature, and he was instrumental in developing the extended freeze-frame zoom at the end of its ultimate sketch, made uncomfortable by a sinister droning hum.This contribution is just one example of what makes Lussenhop an unsung hero of an aesthetic that’s growing more and more popular as mainstream comedy gets more absurd.What probably separated him from others in similar positions, though, is that he would use that footage to remix into his own bizarre videos.It was practice for something, but he didn’t quite know what. ” is returning to television for a Season 6 special.